Eyelid and fornix reconstruction in bilateral abortive cryptophthalmos (Fraser syndrome)

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Isolated Bilateral Complete Cryptophthalmos.

Cryptophthalmos is a rare congenital anomaly, characterized by extension of the skin continuously from forehead onto the cheeks and covering eyeballs. Although cryptophthalmos, as a part of Fraser syndrome, has been reported many times, isolated cryptophthalmos without systemic associations is very rare. We present a 6-month- old child with isolated bilateral complete cryptophthalmos, which to ...

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Syndromic and isolated cryptophthalmos.

Cryptophthalmos is the congenital absence of eyelid with skin passing continuously from the head to the cheeks over a malformed eye. The term cryptophthalmos was coined by Zehender and Manz in 1872, when they first described a patient with bilateral cryptophthalmos and multiple congenital anomalies(l). In 1962 Fraser described 4 cases of cryptophthalmos and multiple malformations in two sibship...

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The cryptophthalmos syndrome.

The cryptophthalmos syndrome, first reported by Zehender and Manz in 1872, and described in detail by Francois, is a systemic congenital malformation characterized by cryptophthalmia in association with craniofacial, otorbinolaryngologic, urogenital and extremity abnormalities. All of the features of the syndrome may not always appear in the same patient. In this report, a ease with cryptophtha...

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Fraser syndrome and cryptophthalmos: review of the diagnostic criteria and evidence for phenotypic modules in complex malformation syndromes.

Fraser syndrome is characterised by cryptophthalmos, cutaneous syndactyly, malformations of the larynx and genitourinary tract, craniofacial dysmorphism, orofacial clefting, mental retardation, and musculoskeletal anomalies. The inheritance is autosomal recessive. No diagnostic cytogenetic abnormalities have been documented in affected patients, and no molecular genetic studies have been report...

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Fraser Syndrome: Two millennia of cryptophthalmos from Pliny the Elder to FRAS, FREM and GRIP: A historical perspective

From its first description in antiquity, the place of cryptophthalmos in the history of medical genetics is briefly set out until, in the twentieth century, this rare constellation of multiple congenital malformations of which cryptophthalmos is the most striking, even though not obligatory, component, was identified as an inherited autosomal recessive condition. It was given the name of Fraser...

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ژورنال

عنوان ژورنال: Australian and New Zealand Journal of Ophthalmology

سال: 1992

ISSN: 0814-9763,1440-1606

DOI: 10.1111/j.1442-9071.1992.tb00704.x